File:Mistletoe Lectin.jpg
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Viscum album agglutinin (VAA-I) consists of two chains. The A-chain (white) with a molecular weight of 29 kDa and with N-glycosidase activity is a potent ribosomal inactivator. The sugar-binding B-chain (green) with a molecular weight of 34 kDa is responsible for the immunomodulatory effect of the molecule. Red colored parts of the B-chain indicate the sugar-binding receptors. (The picture was kindly provided by Madaus Ag, Germany.)
Hajtó, T., Hostanska, K., Berki, T., Pálinkás, L., Boldizsár, F., & Németh, P. (2005). Oncopharmacological perspectives of a plant lectin (Viscum album agglutinin-I): overview of recent results from in vitro experiments and in vivo animal models, and their possible relevance for clinical applications. Evidence-Based Complementary and Alternative Medicine, 2(1), 59–67.
Published by Oxford University Press.
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| current | 05:34, 23 March 2023 | | 432 × 666 (185 KB) | Mhancock (talk | contribs) |
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