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→Scientific Evidence: bussing article
===Meta-analysis===
===Meta-analysis===
[[File:Bussing et al 2012 meta analysis.jpg|none|thumb|214x214px|Meta analysis standard mean difference effects showing an overall treatment effect at SMD = 0.56 (CI: 0.41 to 0.71, ''P'' < .0001), indicating a moderate effect. ]]
[[File:Bussing plausible cause of QOL.jpg|none|thumb|500x500px|Hypothetical diagram explaining the possible mechanisms of ''Viscum album'' extract application on QoL. Büssing, A., Raak, C., & Ostermann, T. (2012). Quality of Life and Related Dimensions in Cancer Patients Treated with Mistletoe Extract (Iscador): A Meta-Analysis. ''Evidence-Based Complementary and Alternative Medicine : ECAM'', ''2012'', 219402. <nowiki>https://doi.org/10.1155/2012/219402</nowiki>]]
Büssing et al examined 734 patients treated with subcutaneous Iscador versus 741 controls in 13 controlled trials (9 of which were randomized) and looked at differences in quality of life.<ref>{{cite journal | vauthors=((Büssing, A.)), ((Raak, C.)), ((Ostermann, T.)) | journal=Evidence-based Complementary and Alternative Medicine : eCAM | title=Quality of Life and Related Dimensions in Cancer Patients Treated with Mistletoe Extract (Iscador): A Meta-Analysis | volume=2012 | pages=219402 | date= 2012 | url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124023/ | doi=10.1155/2012/219402 | access-date=16 March 2023}}</ref> Though the included studies suffered from
quality issues such as lacking description of intention to treat analysis, compliance, and enrolled less than 200 patients, most trials were randomized and all of the results pointed to significant quality of life effects, despite high heterogeneity.
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===Specific Cancer Types===
===Specific Cancer Types===