Changes

European Mistletoe (Viscum Album) is the genus with the most scientific interest. It was used historically in traditional European herbal medicine for non-oncologic conditions including epilepsy, hypertension, and heart failure. In 1917 [[Rudolf Steiner]] together with the physician [[Ita Wegman]] developed and used extracts of mistletoe successfully in a case of metastatic breast cancer.<ref>{{Citation | title=van Emmichoven: Wer War Ita Wegman - Google Scholar | url=https://scholar.google.com/scholar_lookup?title=Wer+War+Ita+Wegman&author=ZJ+van+Emmichoven&publication_year=1992& | access-date=13 March 2023}}</ref>

European Mistletoe (Viscum Album) is the genus with the most scientific interest. It was used historically in traditional European herbal medicine for non-oncologic conditions including epilepsy, hypertension, and heart failure. In 1917 [[Rudolf Steiner]] together with the physician [[Ita Wegman]] developed and used extracts of mistletoe successfully in a case of metastatic breast cancer.<ref>{{Citation | title=van Emmichoven: Wer War Ita Wegman - Google Scholar | url=https://scholar.google.com/scholar_lookup?title=Wer+War+Ita+Wegman&author=ZJ+van+Emmichoven&publication_year=1992& | access-date=13 March 2023}}</ref>

== Bioactive Compounds ==

==Bioactive Compounds==

=== Mistletoe Lectins ===

===Mistletoe Lectins===

Mistletoe lectins are a member of the type 2 RIP (Ribosomal Inhibitory Compound) family, best known for ricin which has a much less cell specific binding preference and thus potent general toxicity. Lectins are agglutinins, meaning that they have the tendency to cause liquid blood into a solid, coagulated state in their pure form.<ref>{{cite book | vauthors=((Cummings, R. D.)), ((L. Schnaar, R.)) | veditors=((Varki, A.)), ((Cummings, R. D.)), ((Esko, J. D.)), ((Stanley, P.)), ((Hart, G. W.)), ((Aebi, M.)), ((Darvill, A. G.)), ((Kinoshita, T.)), ((Packer, N. H.)), ((Prestegard, J. H.)), ((Schnaar, R. L.)), ((Seeberger, P. H.)) | date= 2015 | chapter=Essentials of Glycobiology | title=R-Type Lectins | publisher=Cold Spring Harbor Laboratory Press | edition=3rd | url=http://www.ncbi.nlm.nih.gov/books/NBK453065/}}</ref> The coalescing tendency of mistletoe lectins is thought of in Anthroposophic-Goetheanistic thinking to relate to the nerve-sense system ([[alchemical Sal process]]) which relates to '''crystal forming activity''', '''sensing and directing,''' and in a plant has its orientation in the '''root'''. Mistletoe lectins are found in high concentrations in the haustorium, its root equivalent, and have specific tumor apoptotic effects and immunomodulating effects on the human organism.<ref>{{cite book | date= 2019 | title=Vademecum of Anthroposophic Medicines. Best Practices for Mistletoe Use in Cancer Care. | publisher=Verlag der Gesellschaft Anthroposophischer Arzte in Deutschland | isbn=978-3-946951-06-3}}</ref> Steiner, long prior to the discovery of mistletoe lectins, gave indications that the mistletoe should be specifically harvested in two harvests, one containing the inner parts of the plant, and the other the outer part, and that these extracts be mixed in a specific way.  

Mistletoe lectins are a member of the type 2 RIP (Ribosomal Inhibitory Compound) family, best known for ricin which has a much less cell specific binding preference and thus potent general toxicity. Lectins are agglutinins, meaning that they have the tendency to cause liquid blood to coagulate into a solid state in their pure form.<ref>{{cite book | vauthors=((Cummings, R. D.)), ((L. Schnaar, R.)) | veditors=((Varki, A.)), ((Cummings, R. D.)), ((Esko, J. D.)), ((Stanley, P.)), ((Hart, G. W.)), ((Aebi, M.)), ((Darvill, A. G.)), ((Kinoshita, T.)), ((Packer, N. H.)), ((Prestegard, J. H.)), ((Schnaar, R. L.)), ((Seeberger, P. H.)) | date= 2015 | chapter=Essentials of Glycobiology | title=R-Type Lectins | publisher=Cold Spring Harbor Laboratory Press | edition=3rd | url=http://www.ncbi.nlm.nih.gov/books/NBK453065/}}</ref> The coalescing tendency of mistletoe lectins is thought of in Anthroposophic-Goetheanistic thinking to relate to the nerve-sense system ([[alchemical Sal process]]) which relates to '''crystal forming activity''', '''sensing and directing,''' and in a plant has its orientation in the '''root'''. Mistletoe lectins are found in high concentrations in the haustorium, its root equivalent, and have specific tumor apoptotic effects and immunomodulating effects on the human organism.<ref>{{cite book | date= 2019 | title=Vademecum of Anthroposophic Medicines. Best Practices for Mistletoe Use in Cancer Care. | publisher=Verlag der Gesellschaft Anthroposophischer Arzte in Deutschland | isbn=978-3-946951-06-3}}</ref> Steiner, long prior to the discovery of mistletoe lectins, gave indications that the mistletoe should be specifically harvested in two harvests, one containing the inner parts of the plant, and the other the outer part, and that these extracts be mixed in a specific way.  

==Scientific Evidence==

==Scientific Evidence==