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Repurposed Medications (view source)
Revision as of 22:01, 24 December 2020
, 22:01, 24 December 2020started a page on repurposed medications
Repurposed medicines are medications that are used off label to address a concern. The use of medicines in a repurposed manner encompasses both conventional (broadly accepted) medical practice as well as unconventional medicine. An example of a widely accepted repurposed medicine is misoprostol. This medicine is approved by the FDA for prevention of gastric ulcers<ref>https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/misoprostol-marketed-cytotec-information</ref> but is almost entirely used in obstetrics for induction of labor and to treat postpartum hemorrhage. The REDO Project is a less conventionally accepted approach involving repurposing drugs in oncology. Usual drug candidates are old, inexpensive and with a known safety profile. Much of research is driven in the pharmaceutical world by profit so these inexpensive and off-patent medications might otherwise be left unresearched if not for the efforts of this nonprofit group<ref>http://www.redo-project.org/</ref>. Metformin is an example of one oncology drug candidate that has recently been the subject of more research in oncology with multiple clinical trials ongoing<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497052/</ref>. Jane Mclelland authored a book describing her use of multiple repurposed drugs and supplements in blocking cancer's metabolic pathways. In her case she maintains long remission from stage 4 cervical cancer<ref>[[“How to Starve Cancer : Jane McLelland : 9780951951736.”]]</ref>. The Care Oncology Clinic uses a repurposed drug regimen to augment treatment in cancer patients and these medications and more are used by many other providers as an off label use<ref>https://careoncology.com/</ref>.